If bapi is doing what it is supposed to in terms of reducing the levels of beta amyloid and phospho-tau, and yet not improving cognition nor reversing brain shrinkage, perhaps the whole amyloid hypothesis is flawed.

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The beta period may have been more productive in terms of software tweaks.

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This also means, says Mr Ziff, that beta is not much use to anyone who is not thinking in terms of a total portfolio.

ECONOMIST: Corporate finance