"I think it's very hard, if not impossible, to change body mechanics, " said Dr. Perry Julien, a podiatrist who has treated Olympic runners and serves as the co-medical director of the world's biggest 10K, the Atlanta Peachtree Road Race.
For his followers, 1973 seemed to confirm that in Latin America it was impossible to achieve radical change by democratic means.
The company insists that after careful taste testing, no one will be able to tell the difference and it will taste exactly the same, but given some of the super tasters I have met through my work in the wine and spirits world, I find it virtually impossible that such a change in alcohol content can go unnoticed, especially with no additives to compensate.
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In the end, it should now be clear, fighting back this particular sea change is ultimately impossible.
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Right now, getting guarantees from France and Germany on all this is proving impossible, but that could change in the course of the night, I am told.
When situations are impossible, they have to change.
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It is also impossible to talk seriously about climate change without talking about economic development.
It's impossible to seriously address the climate change problem without involving the major developing countries, India and China especially.
It is technically difficult to figure out how we are going to deal with climate change -- not impossible, but difficult.
But removing the title he actually uses, along with his seat in the House of Lords, is near impossible unless there's a change in the law.
Today, Dr. King's struggle reminds us that while change can sometimes seem impossible, if we maintain our faith in ourselves and in the possibilities of this Nation, there is no challenge we cannot surmount.
He asserted that as a consequence, it will be impossible to resolve the conflict until they change their view of Israel.
But it's impossible to say if social media will change voters' opinions.
Unfortunately the public sector is so large and the poorer states so over-represented in congress that trying to change any of this can appear impossible.
The point is that our limited knowledge and inability to effectively coordinate and apply that knowledge make it impossible to rely on powerful institutions to implement change.
Since it came into being in 1901, Australia's constitution has proved hard to change at referendums, and almost impossible when the prime minister of the day does not support the amendment.
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Change would be difficult, if not impossible, for processes locked into traditional on-site IT systems.
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The idea of long-term tax planning is essentially impossible, since individuals, circumstances and tax laws change with frequency.
With the additional problem of climate change, any significant uptick might be impossible.
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At present, it is impossible for a member of a married couple to change gender and remain legally married.
And once they are exterminated, the ecology of their native reef can change in ways that make their return impossible.
To be sure you are marking a fundamental change in human society borders on the impossible--such events happen just a few times a century, and (barring things like ecological collapse) rarely with anyone's ability to see at the time that anything has changed.
Nevertheless, having spent a pleasant couple of hours up at Girdwood, it was impossible not to be struck by the potential for a change of fortune in the historically troubled north Belfast.
It's impossible for the editors of Forbes.com to predict who will change the world, because major changes are Black Swans, the result of accidents and luck.
But the secret fear of European business is that politics as usual will muddle on and that change will be put off until a crisis makes it impossible to avoid.
They identified two genes - zipper and lgl - which they found worked together to change the make up of sperm cells, making it impossible for them to fertilise uninfected eggs.
The best proof is that we now look back at both the Civil Rights Act of 1964 and the filibuster rule change of 1975 and wonder that they once seemed so impossible.
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