The 32-story hotel has nearly 1, 200 all new and cutting edge guest rooms, all part of the new Respire by Hyatt hypo-allergenic program, featuring a six-stage process to remove irritants, including state-of-the-art air filtration.

FORBES: Hyatt Regency New Orleans, LA

The 210-room Hotel Indigo, part of the IHG chain, is the first LEED-certified hotel in downtown San Diego and offers guests free wi-fi, hypo-allergenic hardwood floors and windows that open to the great outdoors in all rooms.

BBC: Business trip: San Diego