It has four antivirals in human trials and at least another two candidates in the lab.
After studies in primates showed high levels of toxicity from GDNF, Amgen halted further human trials.
Across the drug industry only a trickle of genomics drugs have reached human trials so far.
The deal: They help out with basic research, while aid agencies help pay for human trials.
Sure, these can be done more quickly than human trials, but experiments eat time.
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Their work is in the very preliminary stages, and human trials are only now being planned.
Meanwhile, Japan's Astellas Pharma is in early human trials of another approach to stimulate cancer-cell suicide.
The possibility of liver damage has delayed human trials, but Smith is, as ever, impatient.
They are finishing human trials with Inhale's device and plan to apply for approval by year-end.
The work looked promising in animals, and the researchers wanted to move on to human trials.
Alexza's human trials may fail to replicate the success of the earlier animal study.
They hope to begin implantation in primates soon, which would pave the way for eventual human trials.
But others, including Schering-Plough and Vertex Pharmaceuticals, prevailed and now have protease inhibitors in early human trials.
It has ten other drugs in human trials involving cancers of the breast, colon, brain, ovaries and pancreas.
Now comes the hard part of translating this preliminary result into a vaccine suitable for large-scale human trials.
Animal tests have yielded promising results, and large-scale human trials are expected to kick off in coming months.
In March the FDA rejected Mannkind's first attempt at approval, asking for more information about its human trials.
Proving vitamin D prevents nonbone diseases will require big human trials comparing vitamin D supplements with dummy pills.
This bold promise is based on science done in animals and cells, along with some small human trials.
Now the team intends to examine ways of delivering the genes into humans before finally moving onto human trials.
Essex, advance man for human trials, is spending this fall in Botswana, where 38% of adults are already infected.
Naltrel, as it is known, is in the last phase of human trials.
Without Kosan's technology it would be tough to affordably produce enough quantities of the drug to conduct human trials.
The first two drugs failed in animals and in early stage human trials.
It took six years to design and test a molecule safe and effective enough to go into human trials.
Small human trials to see if berries slow precancerous lesions are under way.
The new studies were the initial human trials of the two PD-1 agents.
All three are in early human trials or are about to begin them.
Some human trials of other probiotics show they modestly reduce the incidence or severity of diarrhea in young kids.
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