Roche's Genentech unit has 25 such agents under development for different cancers, including eight in human studies.
But it was showing promise in these early first-in-human studies in cancer that Engleman was doing with Ron Levy.
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The company is running human studies containing more than 90, 000 patients to prove these medicines prevent heart attacks strokes and deaths.
Thomsen says new data from recently completed two-year human studies of liraglutide show no hints of thyroid problems in roughly 1, 500 patients.
Should it demand additional, longer-term human studies of liraglutide before approving the drug that could reassure people that the risk is low?
It often insists that foods already on supermarket shelves be treated like drugs and run through a gauntlet of preliminary studies before large-scale human studies can begin.
However, as the more cautious of them admit, that cannot be verified until the animal experiments are scaled up to proper, long-term human studies which can verify their hypothesis.
Eleven years later, the Food and Drug Admin-istration has approved the first human studies on the efficacy of MDMA. The tests could begin as early as six months from now.
The company confirmed the researchers' findings, tested the molecule and altered its formulation to make it suitable for humans, and filed an application with the FDA to start human studies.
In 2002 two controlled human studies stunned intensive care specialists by finding that cooling the body temperature 7 degrees helped prevent brain damage in patients whose hearts had stopped and been restarted after cardiac arrest.
Dr Atul Singham, from the Institute of Child Health in London, also said that he was slightly sceptical about the likely scale of "foetal programming" in child diet until it could be proven in human studies.
In its first six months of operation on the station, AMS had accumulated more data on charged cosmic rays than had been previously collected in the history of human physics studies.
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There is growing evidence from human and animal studies that radiation damage can be passed from one generation to the next.
Concern about possible dire health effects from using cell phones stems in large part from the publicizing of certain results from human and laboratory studies as well as from stories about individuals who developed a brain tumor after years of cell phone use.
As a candidate, Bush said he was opposed to using taxpayer money for studies using human embryos.
Doctors at the university will begin studies in human beings later this year.
Always an enthusiastic reader, she pored over Karl Menninger's The Human Mind: case studies of pyromaniacs, kleptomaniacs, schizophrenics and murderers.
Studies of human algesia have established that the musculoskeletal structures most sensitive to painful stimulation are the periosteum and joint capsules.
Olestra is the most tested food substance in history, having undergone more animal studies and human clinical trials than most prescription drugs.
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The book is full of studies in human behavior and those results can help us, and the people we manage, make better decisions.
By 1948 the Nuremberg Code, inspired by revelations of experiments in the Nazi death camps, set standards for medical studies on human subjects.
After receiving her doctorate in 1970, Westheimer began working at Planned Parenthood, where she was inspired to further pursue her studies of human sexuality.
The firm plans to make its facial and skin analyses available as a cloud-based service, allowing for massive opt-in studies of human response to videos and websites.
Through further experiments in human cells and animal studies the researchers found that a protein called NF-kB lured zinc into the immune cells that responded fastest to fight infection.
Dr. Virginia A. Moyer, chair of the task force and professor of pediatrics at Baylor College of Medicine, said the recommendation was based on a recognized modest benefit shown by studies in human subjects.
Beyond that, there were the human (epidemiology) studies.
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"We're kind of glad they didn't do the same thing with the reindeer, because the last thing we would want is reindeer on cocaine, pulling Santa around the sky, " said Cullen, a researcher who studies the human vascular system but was not involved in the Dutch study.
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Personally, I find the studies of early human technology to be absolutely fascinating.
The new studies were the initial human trials of the two PD-1 agents.
Especially when it comes to resveratrol, which has been the subject of numerous rodent studies but very few human ones.
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