Apple again jumped out to a huge lead, but it will lose the war in the end.
The company had a huge lead (in technology world terms) when it came to market with the iPad last year.
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That means that the risk of failure is higher, but that if vorapaxar works, Merck will have a huge lead on the competition.
If it worked, Vertex would have a huge lead in kinase-blockers, but the firm lacked the money to mount a large-scale program alone.
The Clinton campaign claiming an upset victory in Massachusetts, a state where she had a huge lead, all because they had beat Teddy Kennedy.
In October 2003, Dean was building his national and New Hampshire primary numbers in to a huge lead over John Kerry, Dick Gephardt and John Edwards.
De Villiers added 48 to his score of 11 - and the two decisions combined help South Africa build a huge lead over England in Johannesburg.
Everything went perfectly for the Knicks until Smith, while holding the ball on offense with a huge lead, decided to throw his elbow right into Terry's face.
To stand a chance of overturning Mr da Silva's huge lead, he must do two things, according to Gaudencio Torquato, a political scientist at Sao Paulo University.
And we have seen over and over again that the early polls show Hillary Clinton with a huge lead - we saw this in Ohio, we saw this on Texas, we saw this in a lot of big states.
Heidfeld quickly pulled out a huge lead over Barrichello's Honda in second place, and was able to rejoin still ahead of Kubica and fuelled to the end of the race when he made his one and only pit stop on lap 29.
Schalke, ninth in the Bundesliga, never looked like they would throw their huge lead away and on the stroke of half time former Real Madrid striker Raul picked up Jurado's through-ball and rounded Cesar before notching a record 71st Champions League goal.
Williams made his first eight shots from behind the arc, became the first player in a decade to match the opposing team's score in the first half, and was one shy of the league record of 12 3-pointers as the Nets opened a huge early lead and coasted.
The huge reserve may lead investors to worry about other drugs facing litigation--particularly Vioxx, the withdrawn pain pill from Merck (nyse: MRK - news - people ).
He's talking about waves of creative destruction--where huge technological leaps lead to ripping out billions of dollars of old gear and replacing it with billions in new gear, which Matthews is ever ready to sell.
The multinationals, off to a huge head start in the 1990s, retained their lead in the huge Chinese handset market over domestic firms entering the market like TCL, Ningbo Bird, Konka, Datang, Panda, Amiosonic, Longcheer and many others (many firms were former state enterprises that had extensive experience manufacturing TV sets, radios, and pagers).
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In particular, the collapse of Argentina's currency board would lead to huge strains on Hong Kong's similar board.
Key to Qwest's takeover bid is the contention that a merger with MCI would lead to huge cost savings.
At the time the genome was being sequenced, and researchers promised it would quickly lead to huge numbers of breakthrough drugs.
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Pension-fund investors complain that these can lead to huge differences in different private-equity shops' valuations of similar stakes in the same company.
Their size, hierarchy and arcane business practices will lead to huge problems.
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That will either bankrupt insurers or lead to huge rises in premiums.
Such upheaval would typically lead to huge delays and costly overruns.
For years, scientists and space enthusiasts have dreamed that new methods of harnessing solar energy and mining precious metals in space could lead to huge profits.
The internet can provide a vehicle, but passively using it as the destination without digging for input from real, live people can lead to huge wastes of time and resources.
The Rockets, on the other hand, nailed four threes in the period, outscoring New York by nine to take a huge 83-60 lead they never really came close to surrendering.
By early last month, Mr Cardoso's once huge opinion-poll lead over his main, and only menacing, rival, the Workers Party's Luiz Inacio Lula da Silva, had been cut below five points.
After that, while no one reads the same book, this reviewer says The Mobile Wave is about how disruptive technologies lead to huge economic leaps that enhance our health and social wellbeing.
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