Prior to the equaliser, Parkin saw a swinging shot tipped over by home keeper Keiron Westwood.
He reacted quickly after home keeper Boaz Myhill had palmed out Denilson's swerving shot.
However, Antoine-Curier's left-foot effort from the edge of the box trundled towards home keeper Enckelman.
Shrewbury were no more than workmanlike, and home keeper Roger Freestone was redundant in the opening half.
Ryan Giggs and Michael Carrick also had efforts from range to keep home keeper Petr Cech interested.
Home keeper Wayne Hennessey then pulled off a fine save, low to his right, from Aruna Dindane's first-time strike.
Luke Varney also tested home keeper Craig Gordon and Campbell whistled a shot narrowly wide after a purposeful run.
Anichebe curled an effort too close to the prone Scott Carson, and was denied by the home keeper's outstretched foot.
Adebola headed over after just three minutes, while team-mate Andrew Whing directed his diving header straight at home keeper Clayton Ince.
Everton started superbly, with the influential Coleman sending over a dangerous early cross that home keeper Joe Murphy had to push over the bar.
Home keeper Matt Duke saved well from Commons and Bullard went close in stoppage time, but there was no further addition to the score.
Paul Barnes' volley, Simon Marples' free-kick and David Morley's header all forced home keeper Craig Mawson into action in the minutes after the re-start.
Home keeper Craig Wight was forced to pull of decent saves from Brannan, Kevin Twaddle and Lee McCulloch before the match was 20 minutes old.
The home keeper was at full-stretch again to keep out Francisco Sandaza's glancing header, while James McCarthy went close with a strike at the other end.
Sejad Salihovic leveled from the spot and four minutes later had a second penalty opportunity after home keeper Roman Weidenfeller fouled Sven Schipplock and was sent off.
Wednesday raised their game after the interval but despite plenty of possession did not really trouble home keeper Walker, who easily dealt with a 25-yard shot from Alan Quinn.
The turning point came in the second half as Darren Bent won a penalty after being pulled down by home keeper Heurelho Gomes, who appeared lucky to escape a red card.
Their only chance of a lacklustre opening 20 minutes came when home keeper John Filan fumbled a corner under pressure from Abdoulaye Faye and Heskey was forced to clear the danger.
However, the home keeper Neil Alexander, a surprise inclusion for the dropped Allan McGregor, didn't have a save to make until the start of the second half when he rushed to gather at the feet of Clarkson.
Villa left-back Stephen Warnock was almost punished for giving the ball away in the opening minute when Arshavin put Chamakh through before home keeper Brad Friedel came to his team-mate's rescue by blocking at the striker's feet.
But Oxford's 1544 travelling fans were left to rue a great first-half save by home keeper James Bittner to deny 18-goal top scorer James Constable from 12 yards, as well as a disallowed goal by midfield man Alfie Potter.
However, for long periods Arsenal were the better side, but the Gunners rarely tested home keeper Petr Cech, who made two good saves from shots from Andrey Arshavin in the first half and substitute Tomas Rosicky late in the second.
Lecce's hopes appeared over when Juan Cuadrado was sent off for a second booking early in the second half, but the leaders wasted a string of chances before Andrea Bertolacci took advantage of a horrible error by home keeper Gianluigi Buffon to level.
After an uneventful opening, Chelsea launched an innocuous-looking attack with Deco heading on a ball that hugely favoured the home keeper, but when James's kick met air instead of ball due to a large bobble off the turf, Drogba was able to run on and slot into the unguarded net.
The in-form striker, who passed a fitness test before the game on an Achilles injury, collected a pass inside the area from fellow forward Zoltan Gera and stylishly set up a cool, side-foot finish past home keeper Diego Benaglio for his sixth Europa League goal of the season and 19th in total.
Sussex could, have said the same, as James Kirtley dropped home wicket keeper Kieswetter at first slip before he had scored.
The hosts led when an incisive counter-attack saw Nugent race on to a glorious first-time Gelson Fernandes pass and slot home past keeper Frank Fielding.
Watford's second owed more to individual skill as on-loan Arsenal midfielder Lansbury exchanged passes with Cleverley, jinked expertly between two Wednesday defenders and then slotted home under keeper Lee Grant.
BBC: SPORT | Football | Championship | Watford 4-1 Sheffield Wednesday
The Potters then went agonisingly close to a leveller when Whelan walloped a long-range strike against Cech's crossbar with the home side's keeper beaten.
Jordan Owens touched the ball in two minutes later but Paul Munster fired the ball home on 64 after keeper Chris Keenan had spilled a Ferguson shot.
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