"This has got the potential to be the best in class protease inhibitor for HIV and AIDS, " says Palmer, the chief scientific officer.

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The agency says some drugs should never be taken with Mevacor including protease inhibitors, a class of HIV drugs and certain drugs used to treat bacterial and fungal infections.

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Thus far the most promising new class of such enzyme-attacking drugs looks to be protease inhibitors, best known for combating the progress of HIV infections in the body.

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The hepatitis C protease is a particularly tough target because, unlike the similar enzyme in HIV, it has relatively few nooks and crevices into which to cram a druglike chemical.

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