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Companies have insured against turbulence by padding inventories and accepting the high costs of reactive orchestration.
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People with very high C-reactive protein seem to get the most benefit.
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To reach this goal Harvard's Ridker is leading a 15, 000-patient trial testing whether AstraZeneca's statin drug, Crestor, can prevent heart attacks in patients with normal cholesterol levels but high C-reactive protein levels.
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Docs already routinely test for one inflammation-producing protein, high-sensitivity C-reactive protein.
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After a painstaking search for new risk markers, the scientists studied 22, 000 men and found that those with high levels of C-reactive were three times as likely to get heart disease.
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If the FDA adopts the panel's recommendation -- the agency isn't required to do so, but typically does in such cases -- it would mark the first time that a statin was approved for heart-disease-free people with healthy cholesterol levels but other risk factors, including high levels of C-reactive protein (CRP), a marker of inflammation.
CNN: FDA considers statin use for those with normal cholesterol