After testing dozens of prototypes, it found a linker that held tight until it ran across an enzyme present in high quantities in cancer cells, Dr. Siegall says.

WSJ: Drug Conjugates: 'Guided Missiles' to Treat Cancer

In one study of 1, 740 men with high cholesterol, Scottish researchers found that men with high levels of the Lp-PLA2 enzyme had twice the risk of heart attacks, an effect that was statistically independent of their cholesterol levels.

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The researchers think the high death rate from sepsis and shock may have its origin in the digestive system and that using enzyme-blocking drugs may help reduce the harmful effects.

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