The healer had intended for Grant to take this high dose for a few weeks.
The patients were given either Vytorin, or a high dose of generic Zocor, known as simvastatin.
It shows Pfizer's Lipitor prevented heart problems better than a high dose of Bristol's own Pravachol.
Worryingly, even colonies given the high dose may have got off lightly compared with their wild brethren.
But skeptics note that Celebrex, at least at a high dose, did show a risk to the heart.
About one million packs of the pills, which are high dose contraceptive pills, are sold in Britain a year.
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Others were exposed to low doses (half as much as the high dose), or to no dose at all.
The only difference was the dose of atorvastatin and the resulting greater lowering of LDL at the high dose.
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This time the agency asked for a new study to test the effect of a high dose of the drug on heart rhythm.
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Xavier Pi-Sunyer, the Columbia University heart expert who conducted the clinical trial, expects that the high dose would be the one doctors would use.
The high dose MIBG was combined with more standard chemotherapy treatment.
The optimistic case for Zetia is that adding it to a low dose of a statin will lower cholesterol as much as a high dose of the statin, but without the muscle-weakening side effects.
Having considered all these factors, however, the evidence seems clear at this time that high dose vitamin C supplements should be avoided in men, especially if there has been a previous history of kidney stones.
To pull out the most relevant number from that: the decline in distance walked among patients treated with a high dose of the drug was about a tenth as much as for those who were on the low dose.
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Researchers at Harvard simultaneously led an even bigger study testing the same two drugs and found that those on the high dose Lipitor were far less likely to have new heart attacks, strokes or heart procedures than those on Pravachol.
The bottom line is this: why even take the risk of developing a kidney stone-with its attendant pain and suffering-if high dose vitamin C has never been proven to have beneficial effects on our quality of health and risk for developing cardiovascular disease as well as cancer?
Last year, a 10, 000-patient, five-year study of Lipitor, called Treating New Targets, or TNT, showed that the high dose of Lipitor was significantly better at preventing an array of cardiac problems including heart attacks, strokes and surgical procedures than a lower dose (see: " More And More Lipitor").
Vitamin manufacturers are to invited to submit evidence of the efficacy and safety of their high-dose products.
External beam radiation involves zapping a patient with high-dose X rays generated by a machine called a linear accelerator.
Both the high-dose and the low-dose colonies grew more slowly than the undosed ones, gaining 8-12% less weight on average.
Sinai Medical Center, says that one problem with getting patients to take high-dose Lipitor is that some complain about muscle pain.
Doctors may not use a high enough dose of the Zocor component in the Vytorin combo pill to get these other benefits.
New restrictions on the availability of high-dose supplements are one possible solution.
Pfizer, with patent protection for Lipitor until 2010, is conducting a study aiming to prove high-dose Lipitor saves more lives than Zocor, from Merck.
Like many people, I had believed that hospice care hastens death, because patients forgo hospital treatments and are allowed high-dose narcotics to combat pain.
It will also provide a stereotactic radiosurgery service (SRS) which involves the precise delivery of a single fraction of high-dose radiation, usually within the skull.
In only one of the trials did the use of stem-cell support and high-dose chemotherapy appear to prolong life more effectively than conventional low-dose treatment.
One mother featured on the programme was told her son had been prescribed too high a dose of Ritalin and it was to be halved.
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