The tight confines of the airplane gave them especially heavy doses of secondhand smoke.

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Chicago schools suffer, in heavy doses, all the ills of urban school districts: poverty, gang activity and teen pregnancies.

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Some companies that used heavy doses of performance-based pay to compensate their chief executives have also been involved in accounting scandals.

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Intensive feeding combined with heavy doses of chemicals inevitably causes environmental problems.

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Other countries resort to heavy doses of tranquillisers and other calming drugs.

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Where do you find heavy doses of lycopene?

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And sure enough, the retelling of Christ's last days through the eyes of Mary Magdalene is interlaced with heavy doses of modern social activism in this stirring new oratorio, composed by John Adams to a libretto compiled by Peter Sellars from texts both ancient and contemporary.

WSJ: John Adams' staged 'Gospel' has NY premiere

What ails Modesto is what ails Bakersfield (No. 1), Hanford (No. 3), Fresno (No. 4) and other small Central Valley cities (the Valley accounts for all the California cites on the list aside from Los Angeles): heavy doses of nitrogen oxide and hydrocarbons stemming from gasoline, chemical processing, paints and other industrial byproducts that harm the ozone and release particle pollution into the air.

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