For them, Kabul, with its large Persian-speaking Tajik and Hazara community, comes as a culture shock.
The blast ripped through a crowded market place in a Hazara area at around 18:00 (13:00) on Saturday.
BBC: Pakistan blast: Governor fury at 'intelligence failure'
Sunni militant group Laskhar-e-Jhangvi said it had carried out the bombing, which hit a largely Hazara area of Quetta.
Two brazen attacks against a Shiite Hazara community in southwestern city of Quetta killed nearly 200 people since Jan 10.
Some members of the Hazara community took to the streets on Saturday, blocking roads with burning tyres and throwing stones.
BBC: Pakistan blast: Governor fury at 'intelligence failure'
At the blast site, members of the Hazara community helped authorities dig through rubble to find the dead or survivors.
Oxfam, which distributes food in Hazarajat, a central region populated mainly by the Shia Hazara minority, says little has arrived.
ECONOMIST: The race to get food into Afghanistan before winter is on
The BBC's M Ilyas Khan in Islamabad says the group has in the past targeted the area's ethnic Hazara Shia.
Since 2001, the Hazara heartland in central Afghanistan has been among the country's most peaceful areas, largely untouched by the insurgency.
The man told me that he belonged to the Hazara ethnic group and had spent a couple of years in Iran.
The human rights group said more than 125 were killed in Baluchistan province, most of whom belonged to the Hazara community.
Hazarajat, the Hazara-dominated central region (with Behsood district at its eastern extreme), is an area poor in resources with too many people.
On the road to the neighborhood where the attack occurred, Hazara youth burned tires and chanted for the arrests of the killers.
In 2012, more than 400 Shias, most of them belonging to the Hazara community of Balochistan, were killed in targeted attacks by Sunni militants.
"We are demanding the city (protection) be handed over to the army so that the killing of Hazara Shiites can be stopped, " he said.
The Taliban carried out some of their worst atrocities in Bamiyan, singling out the Hazara minority for its adherence to the Shiite branch of Islam.
The demand: The Hazara community called for two main things.
FORBES: In Pakistan, About 100 Dead Remain Unburied Out Of Protest
Sunni extremist groups, some funded by supporters in the Arabian Gulf states, are actively killing Shias in Quetta, who largely belong to the Hazara ethnic group.
Mr Ashraf was due to meet leaders of the city's Hazara community, to which many Shia belong, a senior government official told AFP on condition of anonymity.
Hazara girls have one of the highest high-school graduation rates in the country, and Hazara women have become some of the most visible symbols of the new Afghanistan.
Most of the dead were from Quetta's 500, 000-strong Hazara Shia.
But the Iranians have a particular concern - to protect their fellow Shia Muslims, the minority Hazara community who suffered worst of all at the hands of the Taleban.
But Hazara farmers in Behsood say that the Kuchis' own animals are stripping grasses that the locals need to cut and dry to keep their sheep and goats alive during harsh highland winters.
Mr Karzai is staying his hand only because the IEC balked at accepting the astonishing results from Ghazni, a Pushtun-majority constituency where preliminary counts gave all 11 seats to the Hazara ethnic minority.
If you had your fill with the Kurds and the Sunnis and the Shiites of Iraq, welcome to the warring histories of the Pashtuns, the Uzbeks, the Tajiks, and the Hazara Shiites of Afghanistan.
Mr. Abdul Hameed Chitrali, Database Expert, Hazara University.
However, if the election is to give the political system the sluicing it needs, Mr Dostum and the chief candidate of the Hazara tribe, Mohammad Mohaqiq, who won 11% of the vote, must be overlooked.
ECONOMIST: Hamid Karzai must now put his electoral victory to good use
Much of the violence in Balochistan over the last year have been blamed on Sunni militants attacking members on the minority Shia community, especially the million-strong ethnic Hazara community - who are mainly Shia migrants from Afghanistan.
The four factions negotiating Afghanistan's political future sought to achieve a balance representing Afghanistan's main Pashtun, Tajik, Uzbek and Hazara ethnic groups -- and also women, who have been virtually excluded from public life under the Taliban.
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