Some have expressed doubt about whether Jones can recover from this latest setback, but the combative Welshman says quitting is not in his nature.
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But repeated disappointments have led some experts to doubt whether antisense makes any sense at all.
Some experts have cast doubt on whether the statistical analysis used to interpret the data in the study gives an accurate assessment of true risk.
While I have no doubt missed some, I find it strange that there has been little or no commentary about the large role that inventories have played during the recovery.
If the walls could talk in Dublin's oldest watering holes they would no doubt have some colourful stories to reveal about the city's literary greats trying to release the muse over a few pints.
So this was a downdraft this year, but I have no doubt that at some point in the future we'll rebound once again.
Gov. Parnell will no doubt have to do some political maneuvering of his own to garner support.
Truth be told, all entrepreneurs have moments of self-doubt at some time and those that succeed push through these moments.
And to tie what you guys are doing with what Roger just said about the economy, there is no doubt that we still have some tough sledding before us.
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The company's failure could also have cast doubt on the financial positions of some of Bear Stearns' thousands of counter-parties.
Yet, some of his friends and colleagues have cast doubt on the idyllic image of Pistorius portrayed by the press.
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The company's failure could also have cast doubt on the financial conditions of some of Bear Stearns' many counterparties or of companies with similar businesses and funding practices, impairing the ability of those firms to meet their funding needs or to carry out normal transactions.
It sounds rather painful, and we have no doubt that's a real issue some people suffer from, but considering we've never been diagnosed with such a condition we can't claim that the Whirl Mini alleviated our pain.
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Costs have been reduced, to a level where there is some doubt that any more reductions could be made.
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That some overseas Chinese have been phenomenally successful is not in doubt.
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But judging by the way both teams have crumbled when the stakes are at their highest, some doubt that either club will rise to the occasion.
Given that the unions have so far resisted any shift towards school choice, some may doubt this.
No doubt, he'll have to take on some of his liberal Democrats and sway some of his more conservative party brethren, too.
But yes, some people who have been fair-weather friends, no doubt at those Krug and shepherd's pie parties, will steal away into the night.
And I think there's no doubt the Chinese have come to the rescue to some extent in that they have provided a strong market.
No doubt, many of these have a presence of some sort in the United States, whether via contracts with the U.S. government or operations in this country.
Some, however, still doubt that the internet campaign will have an impact on polling day.
The millions who don't use Skype but have Microsoft computers, phones and video game systems will no doubt see some changes, too.
There's no doubt about that and obviously the selectors are going to have some tough decisions to make in the coming hours.
Dosing levels have crept up by a factor of four over the past decade, though some doubt that this makes dialysis patients live longer.
The report's findings, including extensive testimony from a former conditioning coach who claimed to have injected Clemens with steroids, instills serious doubt as to the validity of some of baseball's greatest accomplishments of the past decade.
Now that some Republicans have begun to share those views, the future of the House probe is in doubt.
But there is little doubt that at some point in time an adjustment of this type will likely have to happen if there is any hope to rebalance this economy.
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