Last week's rally, which sent the Dow up nearly 2%, has made a significant difference.

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Monreal has noticed a significant difference in Garcia over the past few years -- not just physically.

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Starting at the same price as the Roku Media Player, it has at least one significant technical difference.

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Microsoft has invested heavily in its Bing search engine but that has not yet made a significant difference as Microsoft tries to compete with Google and Facebook for consumer mindshare.

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With more than 12, 000 stores across the country, Starbucks has enough scale to make a significant difference.

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Side airbags are another major safety device that's not yet on most vehicles but has been shown to make a significant difference in fatality rates.

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And the reason for that is simply just there is a really important difference of opinion about this that has significant consequences for seniors all across the country.

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Research at two universities (by Professor Sonja Lyubomirsky, and by Professor Laura King) has shown this small investment of time can make a significant difference in your life.

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Eric Topol, a cardiologist at the Cleveland Clinic, says he has reanalyzed that data, and found the difference to be significant, if small.

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However, Mr Morris has expressed "disappointment" and claimed it would not make a significant difference.

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