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So it is hardly surprising that the number of vaccines moving through the pipeline to large-scale trials has been small, and their progress sluggish.
ECONOMIST: AIDS vaccines on trial | The
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Using the technology, they were able to share their experiences with fellow miners in Ghana, where small-scale mining has been going on for years.
BBC: NEWS | Technology | Miners tap into video goldmine
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In three years, Ebay stock has been up and down in on a very small scale compared to other companies such as Amazon.
FORBES: eBay's Marketplace Business Still A Question Mark
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Most of it has been wind power, but wind is still small-scale and relatively expensive.
WSJ: Daniel Yergin on the Shale Gas Revolution: Stepping on the Gas
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In fact, Mendoza says, the response has been so overwhelming that what was originally just intended as a small-scale promotion involving local sponsors and a handful of homes is being expanded to the national level.
FORBES: From April Fool's Joke to Mobile Advertising Reality
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This has been spent, not just on roads, bridges and business parks, but on small- scale schemes such as village-owned forests to help keep remote communities alive.
ECONOMIST: Highlands
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There is no doubt that the industry has structural problems, it is on a relatively small scale, until now there's been little interconnection with the British mainland and the Irish Republic, and much of the infrastructure is getting old.
BBC: A highly charged debate
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The row over quarrying at the site began after permission for a small scale operation was granted by the then Stirling District Council in 1982, however there has been little activity at the site for the past 14 years.
BBC: Stirling Council suspends quarrying at Bannockburn site