Fly-half Flood suffered a shoulder injury against France, while flanker Worsley suffered a gashed right thumb.
England team manager Martin Johnson will be relieved fly-half Flood came through the clash without injury, as did lock Louis Deacon.
England flanker James Haskell and fly-half Toby Flood could not hide their disappointment.
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Only a perfect kicking performance by fly-half Toby Flood, who nailed all six of his attempts, kept England in control.
Fly-half Toby Flood and flanker Joe Worsley, who picked up injuries in the emphatic 34-10 victory over France on Sunday, are passed fit to play.
According to the National Weather Service, nearly half of all flood related deaths occur in vehicles.
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According to the National Weather Service, nearly half of all flood-related deaths occur in vehicles.
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Robshaw returned but still his side had difficulty in breaking out of their half, with Flood narrowly denied after an excellent break.
Leicester, with South African Derrick Hougaard at fly-half instead of Flood, won 19-15 against Bath, while the Blues beat Sale thanks to a last-minute try from Richard Mustoe.
Case in point: fewer than half the residents in flood and hurricane-prone areas were insured against water damage from Hurricane Katrina and Hurricane Sandy.
The Tigers trailed 17-16 at half-time, Toby Flood's early try cancelled out by tries from Danny Care and George Lowe.
When the levees broke and flood waters sent half the town fleeing, the Crescent City was a study in urban dysfunction.
Of the 5.6 million people with flood insurance coverage, roughly 1 million get it for less than half the true price, because they live in houses built before flood hazard maps were created.
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Flood was replaced just before half-time on Sunday after landing awkwardly on his shoulder in the lead up to Worsley's try.
Flood played at fly-half in England's last match, the defeat by New Zealand in the second Test in Christchurch in June.
The hosts were fortunate to be 6-6 at half-time, courtesy of Toby Flood, as South Africa dominated but managed only two Morne Steyn penalty kicks.
Boro continued to shade the first-half and could have gone ahead when Flood teed up Killen for a shot which he wastefully lofted over the bar.
Cipriani will compete with Leicester's Toby Flood for the fly-half shirt while Abendanon, who has been in eye-catching form for Bath, will provide extra competiton at full-back.
They finally managed to get on the board through a Flood penalty but a bad half continued for the visitors as they lost Ben Youngs to the sin-bin.
Saracens were leading the Tigers 6-3 at the interval in Saturday's match, but the league leaders were overhauled with Toby Flood kicking four second-half penalties for the visitors.
Only about half of property owners in New Orleans hold flood coverage, and even fewer in hard-hit patches of Mississippi and Alabama.
In the injury-enforced absence of Jonny Wilkinson and Toby Flood, uncapped Leicester fly-half Sam Vesty and Brive's Andy Goode were selected ahead of Cipriani for the senior squad.
England are still very negative, but the midfield balance was better with Riki Flutey and Mike Tindall, while Toby Flood offered something at fly-half when he replaced Andy Goode.
He last played international rugby nine months ago when he replaced Toby Flood during the 33-10 victory over Ireland and has seen Danny Cipriani and Flood take over England fly-half duties during the second half of this year.
Jonny Wilkinson is out with a hamstring injury, meaning Newcastle colleague Toby Flood gets another start at fly-half.
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Meanwhile Jonny Wilkinson has been reflecting on his demotion to the England bench, with Toby Flood preferred to the Toulon fly-half.
However, it took the hosts over half an hour for their first score, with Flood providing a neat inside pass to Tuqiri.
Toby Flood replaces Charlie Hodgson at fly-half, Jamie Noon partners Mike Tindall at centre while Mathew Tait and Tom Varndell come into the back three.
Mr Bathmaker said the new design was much simpler, with half the number of foundations, which reduced the flood risk, and a swing section for river traffic.
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