Cillian Sheridan doubled the lead in the second-half with a tap-in and John Sutton's close-range strike completed the rout four minutes from time.
Anthony Allen denied Mathew Tait, playing at full-back for the third time since the World Cup, a try just after half-time with a great tap-tackle 15m out, after Tait had chipped ahead and gathered his own kick.
The Ospreys hit back with former All Blacks scrum-half Justin Marshall taking a quick tap and offloading to Jason Spice who sent Connor in for a well-worked try.
But from the next line-out Ireland scrum-half Peter Stringer took a quick tap off the top and scampered through the Scottish defence before offloading to Heaslip, a first-half replacement for number eight Denis Leamy, to crash over.
Scrum-half Eoin Reddan took a quick tap on England's 22, feeding the ball quickly out to the left.
The home side were stunned in the opening five minutes when Thomas crashed over for his score following a quick tap penalty by scrum-half Gareth Cooper.
McAllister's second successful penalty reduced Munster's lead to 19-9 and Sale seemed to be back in it on 51 minutes when Hodgson scored in the corner after a quick tap from replacement scrum-half Dwayne Peel.
But there was little possibility that Fletcher would miss after an unfortunate ricochet off Dean Whitehead presented the United midfielder with the simplest of tap-ins shortly after the half-hour mark.
Graham then appeared set to double Swansea's advantage before half-time but Ward's intervention nicked the ball off his toe as he waited for a tap-in at the far post.
Halfpenny seemed set to sneak in at the corner flag, only for his foot to be dragged into touch by a flying tap-tackle from Edinburgh scrum-half Mike Blair.
Bellamy's low cross then gave Joe Ledley a simple tap in to double Wales' lead 10 minutes before half-time.
Caerphilly made several changes at half-time and had the better of the early action, but despite several close calls failed to tap a solid Ponty defence.
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