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These patients have tumors with a mutation in a growth-promoting gene called kras that may render the drugs ineffective.
FORBES: ImClone's Gene Test Battle
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In 2002 gene researchers in the U.K. discovered that two-thirds of melanomas have a mutation in a growth-promoting gene inside skin cells called BRAF.
FORBES: Targeting Melanoma
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But the gene scan found the tumor was making large amounts of a growth-promoting protein called RET.
FORBES: Health