John XXIII was famed for calling the Second Vatican Council in 1962, which ushered in great changes in the Roman Catholic Church's relationship with the modern world.
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During the dinosaurs' time on Earth, "the atmosphere became charged with methane, which finally damaged the ozone layer and brought about great changes in the vegetation, " it added.
It's a great example of changes in public spending affecting the private sector.
But now we see great hesitation in making changes that could affect large numbers of people.
Great Yarmouth Borough Council said changes in government funding meant it had to cut costs from 2014.
The risks are greatly magnified because all of the projected population increases will occur in less-developed regions that will have great difficulties in absorbing the changes.
The bureau's Rose Henderson said letters were sent out to claimants in Great Britain in 2011 to warn them of proposed changes which would come into effect in April 2012.
Mrs Foster said the reform of credit unions in Northern Ireland would follow the example set by recent changes to credit union regulations in Great Britain.
We have followed with great interest and empathy the profound changes in North Africa and in the Arab world.
We have talked in great detail with doctors about the changes ahead, and privately about our personal feelings.
We believe this is possible, given the changes in how we work and the great successes we have had building our digital readership lately.
She admitted, though, to great uncertainty over the negotiations in the short term, with coming leadership changes in the US and China.
Kansas and the rest of Great Plains also represent the part of America best positioned to benefit from changes in the global economy.
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He acknowledged that "there are great leaders in all schools, including challenging schools" and added that changes to the Ofsted framework were designed to focus inspections on the "value added" - how much progress pupils make from when they arrive at the school.
In his book The Great Stagnation Cowen says his grandmother saw greater changes.
Few of the changes in the handling and presenting of animals would be possible had great progress not come in veterinary care.
Mr. President, your leadership of this great nation of the United States coincides with a time of profound changes taking place in the world at large.
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"We believe that this important reorganization of our key business units will help us raise our operating leverage across the firm and realize the full potential of Morgan Stanley's great franchise, " Purcell said in a statement announcing Monday's management changes.
The great marker of the societal changes over the past couple of generations has been the rise in the female employment rate.
Because of the great difficulty and cost associated with this type of drilling, it is very susceptible to changes in oil company budgets and the price of oil.
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With all of the legislative changes around compensation, this is a great time to talk with your shareholders about the year in review.
Lord Robert May, the current president of the Royal Society, said the Aventis Prizes celebrated the "great communicators" who helped the world come to terms with the rapid changes brought about by developments in science.
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The ne plus ultra of free jazz, Ayler performed the musical equivalent of speaking in tongues: he left chord changes and swinging rhythms far behind and emitted great spiritual wails and shrieks from his horn.
And those changes were felt particularly in suburban communities because some of the hardest hit industries in the Great Recession were these more suburbanized types of jobs, like construction, like services, like manufacturing.
Studies of Australia's Great Barrier Reef show that levels of calcification are down, though it is not yet possible to say changes in chemistry are a reason for this.
Professor Al Aynsley-Green, of Great Ormond Street Hospital, said the finding was not surprising, given the magnitude of changes that took place in the body's systems in the period immediately after birth.
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