Patients on Januvia experienced slight weight loss, while those on Glucovance gained an average of 2.4 pounds.

FORBES: Diabetes Duel

Many analysts expect the two drug makers to eventually try to replace medicines like Glucovance as first-line treatments against diabetes.

FORBES: Diabetes Duel

The usual defense of this is to switch patients to new versions of the drug, including Bristol's Glucophage XR and Glucovance.

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Those taking Glucovance only saw their risk of diabetes decrease 31%.

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