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Ariads scientists will try to prod the gene into producing more or less bone formation protein, switching the gene on and off.
FORBES: A hail of silver bullets
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HERC2 has no effect on eye color, but it contains an unexpressed segment of DNA that is needed for the switching on of a nearby gene called OCA2, as demonstrated by newly published work by Robert-Jan Palstra and others at Erasmus University in the Netherlands.
WSJ: Matt Ridley on Human Culture's Effect on Genes | Mind & Matter
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Although Monsanto has promised to put its terminator-gene system in deep-freeze, the molecular switching that underlies it remains a hot topic at many of the world's leading agri-biotechnology firms.
ECONOMIST: Terminator genes