To get a new gene count, Velculescu and his colleagues used a different technology called serial analysis of gene expression (SAGE), which was developed at Johns Hopkins University and licensed to Cambridge, Mass.

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The Rosetta purchase gave Merck expertise in figuring out exactly which genes the body is reading--a technology called gene-expression profiling.

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Rudolf Jaenisch. (Applause.) The 2010 National Medal of Science to Rudolph Jaenisch, Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, for improving our understanding of epigenetic regulation of gene expression, the biological mechanisms that affect how genetic information is variably expressed.

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