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Many of gene therapy's other problems have been with the vector that carries the gene, usually a virus.
ECONOMIST: The prospects for using genes as a therapy may be improving
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Brin became passionate about the cause in 2005 when he discovered he carries the flawed gene that gives him a 50% chance of developing the brain disease.
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In a New York Times op ed yesterday, superstar actress Angelina Jolie, 37, described how she carries the BRCA1 gene which, her doctors said, put her at an 87% risk of developing breast cancer, and a 50% risk of getting ovarian cancer.
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Ms. Jolie said that after genetic testing she learned she carries the "faulty" BRCA1 gene and had an 87% chance of getting the disease herself.
WSJ: Angelina Jolie Says She Had Double Mastectomy
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Jolie said that after genetic testing she learned she carries the "faulty" BRCA1 gene and had an 87 percent chance of getting the disease herself.
WSJ: Angelina Jolie says she had double mastectomy
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The 37-year-old actress previously said she decided to have the double mastectomy followed by reconstructive surgery after learning she carries a mutation of the BRCA1 gene, which sharply increases her risk of developing breast and ovarian cancer.
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When a cell translates a gene into a protein, it uses a messenger molecule that carries the genetic information to a protein factory called a ribosome.
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It aims to muffle the gene for a protein called apoliprotein B, or ApoB, that carries fatty cholesterol to the arteries, creating thick plaques.
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