Ashleigh Griffin ( 2008 FWIS Fellow), Elizabeth Murchison ( 2009 FWIS Fellow), Araxi Urrutia ( 2007 FWIS Fellow) and Patricia Alireza ( 2009 FWIS Fellow) provided fascinating insights into their work on the behaviour of bacteria living in the lungs of cystic fibrosis patients, transmissible cancers in Tasmanian Devils, human gene and genome evolution and the effects of high pressure at quantum level.
Church, who started the Personal Genome Project and is founder of the gene-scanning company Knome, envisions a Wikipedia-style model for interpreting the genome, where experts (using their real namea) collaborate online to help people interpret their genome results.
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If there are other promoters involved, they do not affect the tendency of the gene itself to fragment and move around the genome.
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To make the mice glow red, they inserted a gene taken from coral and inserted it into the mouse genome.
Two developed the disease because IL2RG inserted itself into the cellular genome next to a known cancer-causing gene and activated it, but the cause of the third cancer case had not been found.
Love insists that Hyseq has a unique gene-finding technology that will help it discover genes that have been missed both by other gene database companies and by the U.S. government-funded Human Genome Project.
What make better tests possible are gene databases, first developed in the early 1990s by Human Genome Sciences and Incyte Genomics, that categorize thousands of genes by the type of diseased tissue they inhabit.
It turned out that the virus used to deliver the gene therapy was also inserting itself into cancer-causing areas of the genome, and not just where it was needed to cure the kids.
It is the company that was founded by gene guru Craig Venter that was going to beat the government at deciphering the genome and become the Bloomberg of biology by selling genetic data.
This one gene is the longest of the 25, 000 that make up the human genome, and it consists of 2.2 million "letters" (A, T, G and C for four different nucleic acids), which spell out the recipe for making the muscle protein.
As such, they are signposts along the genome that provide clues to what version of a gene a person may have, and whether it's been linked to some particular disease.
But rather than using nets and chloroform, their tools are the high-speed gene-sequencing machines developed for the Human Genome Project.
But Love says he thinks the genome maps miss a significant number of genes that Hyseq has found and says their gene-finding algorithms were perhaps at fault.
Here, we ask Nobel laureate James Watson, the co-discoverer of the structure of DNA and one of the first people to have his genome sequenced, to pick his favorite gene.
Over the last six months, New York State's Department of Health has sent letters raising the specter of fines and jail time to six online gene-testing firms that offer consumers the ability to peer into their genome to assess their future risk of getting diseases such as cancer, heart disease and multiple sclerosis.
While GSK's partner Human Genome Sciences invented the drug, Glaxo invested in HGS' gene-hunting technology back in 1993 and stayed the course even after murky early results.
Twenty-two years ago Francis Collins, who would go on to head the Human Genome Project and run the National Institutes of Health, was part of a team that found the gene that, when mutated, caused cystic fibrosis, a deadly childhood disease in which the lungs fill with mucus and the pancreas does not make digestive enzymes.
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