Vandeweghe defeated Italy's Tathiana Garbin 6-4 6-4 for her first victory in a WTA Tour main-draw match.

CNN: Sharapova on song as L.A. seeds tumble

The Slovakian will next face another Russian following Anastasia Pavlyuchenkova's 4-6 6-1 6-2 win over Tathiana Garbin of Italy.

CNN: STORY HIGHLIGHTS

Second seed Amelie Mauresmo of France beat Tathiana Garbin 6-2 6-1 and US Open champion Svetlana Kuznetsova defeated Czech Eva Birnerova 6-3 6-2.

BBC: SPORT | Tennis | Clijsters eases into third round

But fourth seed Ana Ivanovic was in sensational form as she crushed Tathiana Garbin 6-0 6-3 in the opening match of Wednesday's night session.

BBC: Venus stumbles into third round

In other action, Shenay Perry, a 19-year-old American, beat Virginia Ruano-Pasqual of Spain 6-4 6-3, while Tathiana Garbin of Italy upset sixth-seeded American Laura Granville 7-6 6-1.

BBC: SPORT | Tennis | Pratt eases through