" Adds Curt Furberg, from Wake Forest University: "In the U.S., we don't take action.
"Either the company suppressed or the FDA was asleep, " argues Curt Furberg of Wake Forest University Baptist Medical Center.
Curt Furberg of Wake Forest University, had written scathing editorials about Bextra and Vioxx, yet was allowed to serve on the panel.
Furberg writes that the 18-month difference is "almost gone, " and asks whether the complete data were available to the authors before the article was published.
Furberg has co-authored epidemiologic studies that showed problems for Bextra, and he was the harshest Pfizer critic on the panel--at one point saying inconsistencies in the company's data submissions smacked of dishonesty.
Wake Forest's Furberg says further analyses of the data that are now ongoing are only likely to further weaken the claim that there is a delay in Vioxx's affect on the heart.
Curt Furberg, a professor at Wake Forest University and another longtime critic, says that based on new data that has been made available, "there is no evidence whatsoever" for an 18-month delay.
Steven Nissen of the Cleveland Clinic, who called attention to clinical data that indicated a heart risk for Vioxx and Celebrex in 2001, is also on board, as is Curt Furberg of Wake Forest University.
In an editorial in the American Heart Journal, where the MEDAL design was recently published, Curt Furberg of Wake Forest University wrote that there is "no scientific support" for handling the data in this way.
Thus, it was both surprising and disturbing to read a recent piece in the Journal of the American Medical Association by Moore and Furberg which essentially calls into question the value of this program.
In an editorial in the New England Journal, two other veterans of the Vioxx controversy--Bruce Psaty of the University of Washington and Curt Furberg of Wake Forest University--write that there is no clear reason to prescribe Avandia at all now.
In a separate New England Journal editorial, University of Washington epidemiologist Bruce Psaty and Wake Forest University's Curt Furberg are also harshly critical of Pfizer for not publicizing details until just a few weeks ago of another study that found hints of cardiovascular problems with Celebrex in 2000.
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