But one of the most anticipated guests is someone who might or might not show up, which is kind of how it's always been for the '70s funk rock icon Sly Stone.
Their distinctive mix of rock, funk and world beats earned Talking Heads a place in the Rock and Roll Hall of Fame last year.
The Los Angeles-born-and-bred band Fishbone, which delivered a bracing combination of rock, funk, punk, and ska, was one of the brightest lights of late-eighties alternative rock.
Louder and usually less talented rock and funk acts are there on other nights.
With high ceilings, clear sightlines, multi-level balconies and three bars, Union Transfer is attracting top national and international talent in genres as varied as rock, funk, rap and hip hop.
Guest host Mary Louise Kelly speaks with Adam Levine and Jesse Carmichael about the group's new and third studio album, "Hands All Over, " which is a mix of funk, soul, rock and country.
On Sunday we begin with We The Undersigned, aka WtU. They are a Liverpool based collective that play a high energy mix of Reggae, Rock, Funk, Jazz and Hip Hop, topped with a four piece brass section.
The eclectic mix of blues-rock and psychedelic-funk tracks includes "Mojo Man" which opens with a big Ronettes beat before lurching into a Memphis horn grind.
The compositions are all original, a contrast to the MGs' previous record, McLemore Avenue, an instrumental re-imagining of The Beatles' Abbey Road, and they touch on a range of styles, from agitated funk to thick and humid swamp-rock songs like "Fuquawi" (audio), which features Cropper at his most devastating.
Several numbers from his 2012 disc, the finely textured "Shifty Adventures in Nookie Wood, " allowed Mr. Cale to demonstrate how its funk rhythms and droning, burbling electronic core suggest another way to present modern rock in a forward-looking yet accessible form.
Their rock-infused interpretation of the blues and folk genres also incorporated rockabilly, reggae, soul and funk among other influences, it adds.
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