Steven Reid put the hosts in front with a header from Chris Brunt's corner.
The dangerous Stephen Garrett almost put the Reds in front but his header was cleared off the line.
Craig Thomson, back in the Hearts defence along with fit-again Ismael Bouzid, was proving a threat from left-back and his curling cross found Suso, but the Spaniard's front-post header flew wide from 16 yards.
But there was nothing the Owls keeper could do to prevent Lee from putting the visiting side in front with a powerful header from six yards when the striker rose unchallenged to meet Ambrose's corner after 24 minutes.
Alan Lee had put Palace in front with a thunderous header but Leon Clarke equalised close to the break with a superb strike, although the Eagles felt he should have been penalised for a foul on Danny Butterfield in the build-up.
Yet PSV got themselves in front when Mascherano missed his header as he tried to clear a corner and the ball fell for Lazovic, who stroked the ball past Cavalieri.
But the Bairns came roaring back before the break with a cool finish from Pedro Moutinho levelling matters and Darren Barr's header putting them in front.
When Mills' header put Reading in front for a second time, Paulo Sousa's side were unable to come back - as in the dying stages Federici pushed away a headed effort from Moreno and then parried a Fryatt shot.
The visitors were hanging on, with Brian McBride isolated up front, though Carlos Bocanegra's header from a corner, well saved by David James, sparked a period of greater composure.
But a Ba double and a Carlton Cole header denied West Brom victory in front of their new boss Roy Hodgson.
Sunderland should have equalised almost immediately when an Andy Reid cross found Cisse unmarked in front of goal, but he planted his header wide.
Kyle Walker's long-range strike put the hosts back in front only for Clint Dempsey's late header to give the visitors a share of the spoils.
Sebastian Rudy slotted the visitors in front early on and Zdravko Kuzmanovic powered in a header on 59 minutes.
An unmarked Crouch volleyed Tottenham in front before Jermain Defoe extended their lead with a header after Andy Lonergan saved his initial shot.
The Dutch side seemed to be on their way out after Sergey Kovalchuk's second-minute header put Spartak's noses in front going into the final 10 minutes.
They could have gone in front inside 15 seconds when Brede Hangeland's header was superbly tipped over by Andriy Pyatov, but the Cottagers only had to wait two more minutes to nudge ahead.
But chances continued to come for Spurs, and Berbatov in particular, as he found himself in plenty of space following a corner but his header was cleared by Schmitz a yard in front of the line.
And it was Rangers who got their noses in front when Davis pounced upon Charlie Mulgrew's defensive header, drove at the Celtic defence and guided a low left-foot shot into the net via the post in the 24th minute.
Shefki Kuqi got in front of his marker to flick it on and Paul McLaren thumped a header against the outside of the post.
Leeds stormed back as Becchio nodded in George McCartney's cross to equalise and they were soon in front as Bruce took full advantage of Sean St Ledger's poor header.
Stefan Klos kept Rangers in front when Martyn Corrigan met Steven Hammell's free kick with a header from six yards only for the German to block the effort with his chest.
James Morrison headed the Baggies in front before Mark Noble tapped in a rebound from David Di Michele's header.
The Brazilian's form in front of goal has often been less than top quality, and his misdirected header when totally unmarked will not have boosted his chances of remaining at Arsenal after this season.
BBC: Portsmouth and Arsenal found each other hard to break down
Celtic almost went in front when Kris Commons' teasing cross found Brown diving in but the skipper's header flew past the post.
Nikola Kalinic put Rovers ahead from six yards before a header from substitute Didier Drogba and Salomon Kalou's finish sent Chelsea in front.
Paul Scharner's diving header was well saved by keeper Paul Robinson and Kilbane headed over with a gaping goal in front of him.
United went closer still on the stroke of half-time when Conway flighted a free-kick to the front post and, although Daly connected a head of Kello, the Irishman's powerful, close-range header struck the outside of the post.
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