To make it injectable, the National Cancer Institute had to dissolve it in an egg-based formulation with a nauseating smell.
Had this been a private-sector enterprise, competition and the threat of liability would have spurred innovation in the form of frequent updating of the drug's purification and formulation with state-of-the art technologies and would have required rigorous adherence to government regulations.
The latest part of the study, which involved about 4, 000 participants, also looked at the effect of replacing beta-carotene in the supplements formulation with lutein and zeaxanthin because of studies that found former smokers who take beta-carotene have a higher incidence of lung cancer.
Members of the Senate, I could not disagree more with that formulation of this issue.
But six physicists - including Higgs - are now generally credited with the formulation of the concept.
BBC: Peter Higgs: honour for physicist who proposed particle
Eventually, a Brazilian diplomat came up with the formulation that the deal must have "legal force", which proved acceptable.
However, the problem I have with that formulation is that it makes the implicit assumption that the current distribution is correct.
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The problem with this formulation is that, in the process of purportedly closing one loophole, it would appear to create new ones.
But there were, for Gillis, some mitigating factors that eventually led him to his current formulation of artistic rigor with good-time danceability.
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There are those, however, who should know better than most about the ongoing seriousness of the threat, among them those lawmakers tasked specifically with the formulation and oversight of counter-terrorism policy.
They hired a scientist to come up with a formulation of chemicals that delivered nitrogen, potassium and phosphorus in highly water-soluble form, so that an impatient gardener could give plants an instant shot to the leaves, so to speak.
From the West he acquired an understanding of Greek metaphysics, with its remarkable formulation of body and soul.
The only problem with this neat little formulation is that it is wrong at every level.
In the original formulation the teller had access to the customer with the big paycheck and merely had to steer him down the hall for the bank to make a second fee by managing his portfolio.
Silicon Valley is always evolving, like an active volcano that erupts every few years with creative destruction that brings forth a new formulation of ideas, technologies, and commercialization.
During project formulation and implementation, UNESCO-IHP will collaborate closely with a wide variety of partners - representing all stakeholders at all levels having strong experience in groundwater governance - which will join the Permanent Consultation Mechanism (PCM).
The EBA said it recommends that these banks be forced by their respective national regulators to raise additional capital as a protection against possible further losses from loans going bad, with a deadline of 15 October for the formulation of remedial plans and 15 April 2012 for implementation.
The effects of aspirin were independent of age, and sex, and were also seen with a low-dose, slow-release formulation of aspirin designed to inhibit platelets but to have little systemic bioavailability.
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Contribute to the mobilization of extra-budgetary funding for new programmes and projects in line with the priorities of the Section, to the formulation of project documents and to the coordination of periodic reporting to the donors.
Yet, while there are now many books and ideas about strategy formulation, there is very little research about how to link strategy with the nitty-gritty of sales execution.
The company confirmed the researchers' findings, tested the molecule and altered its formulation to make it suitable for humans, and filed an application with the FDA to start human studies.
Rather than being magnesium based it seems to be zirconium with copper, nickel and niobium (that latter in only one formulation I think).
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The initial formulation was based on the concern that the United States might need to deal with aggression at the same time in both Southwest and Northeast Asia.
Because most small-molecule drugs can be manufactured with easily replicable chemical processes that lead to a largely reproducible drug formulation, the clinical trial data that supported approval of the original version can be relied upon for the generic versions.
Among Schering's pipeline drugs are a new formulation of Taxol, for breast cancer, and a drug co-developed with Novartis that was hoped to be a pill version of Genentech 's (nyse: DNA - news - people ) Avastin.
The programme will also promote the development of new STI indicators in order to better respond to the specific needs of Member States within their different social, economic and cultural contexts with an overall aim to providing country appropriate policy advice on the formulation and implementation of STI policies, strategies and plans that contribute to building peace, inclusive societies and sustainable development.
Unless there's some formulation in which Enbrel and Kineret are more effective when used in combination, that leaves Amgen with two compounds that compete against one another--a point that could be confusing when marketing the treatments to doctors.
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