In 1776, George Washington unveiled the Grand UnionFlag, the first national flag in America after King George III of England called on American forces to surrender.
Deputy First Minister Martin McGuinness has said the unionflag dispute and dissident republican violence underline the need for more political engagement.
Ms Villiers told the House of Commons 66 police officers had been injured since violence first flared up following the decision to restrict the flying of the unionflag at Belfast City Hall.
His mission will make him the first UK national to live and work in space, and to fly the Unionflag, on a British-government-funded programme (the UK is Esa's third largest contributor).