Anderson reaped instant success as Shane Watson edged a simple catch to Swann at first slip and Tim Paine, fresh from a maiden one-day ton at Trent Bridge in the previous match, followed suit to give Onions his first one-day wicket for England.
The first one-day international will be held in Vadodara, western India, on 25 October.
"It was great to see him get his first one-day international hundred, " said Ponting.
They began their first one-day strike last Friday and have three more days of industrial action planned.
Ireland skipper Trent Johnston was delighted with his team's performance in their historic first one-day international against England.
BBC: SPORT | Cricket | England | Strauss pleased to begin with win
Middlesex captain Strauss could debut in Tuesday's first one-day international after opener Vikram Solanki was again dismissed without scoring.
BBC: SPORT | Cricket | Sri v Eng | Strauss stars for England
So why, you may wonder, is our first one-day event in a gritty, depressed, financially-troubled city that seems well past its glory?
So does that mean Mr McCrea could be first minister one day?
BBC: Basil McCrea wants to be Northern Ireland's first minister
The controversy surrounded umpire Peter Hartley, standing in his first one-day international.
Mascarenhas captured his first one-day international wicket with the key scalp of Dravid, who swept and was expertly taken by Prior at the stumps.
Whatever the result in the final match, Fletcher will be able to point to England's first one-day series win for three years and nine tournaments.
Klusener and spinner Nicky Boje suffered the heaviest punishment as first Elahi and then Razzaq - with his first one-day hundred - reached three figures.
And, when the rain set in, despite striking 13 fours and three sixes from his 90 balls, that left a frustrated Gatting just one short of that first one-day ton.
But the problems were all with the bat - and there will be obvious concerns for England with the first one-day international of seven looming large in Rajkot on Friday.
Moeen Ali, who had earlier hit 51, his first one-day half-century of the season at New Road, ran round the deep midwicket boundary to brilliantly hold onto a chance from Chris Nash.
New South Wales bowler Hazlewood, 19, played for Australia in June's first one-day international against England at the Rose Bowl, taking the wicket of Craig Kieswetter to finish with 1-41 from seven overs.
And, exactly 40 years after the first one-day international was played on the same ground, Watson appropriately produced the winning hit, smashing the first ball of the final over for six over long-on.
But Newton followed her 59 in the first game with another confident innings and she received good support from Jenny Gunn (49) and Atkins, who made 32 in her first one-day appearance since 2002.
BBC: SPORT | Cricket | Women's cricket | England women earn series victory
Meanwhile, Farbrace is hoping that the England selectors will keep faith with batsman Joe Denly for the first one-day match on Friday, despite his disappointing display with the bat so far in South Africa.
Southee then removed Cameron White (six) and Adam Voges (five) while Nathan McCullum picked up his first one-day wicket when he had opener Shane Watson (53) caught by Taylor to leave the tourists 96-5.
Adam Gilchrist was trapped lbw by Kyle Mills on the third ball of the match and Chris Martin celebrated his first one-day match in five years by snapping up Simon Katich in his second over.
Although England lost the Test series 1-0 they then won their first one-day series win in the Caribbean and Flower's good relationship with Strauss has helped to make him the leading candidate for the permanent role.
When the patient crowd was finally rewarded with some action, England lost skipper Andrew Strauss to the first ball of the second over as Ravi Rampaul made an immediate impact in his first one-day international for over a year.
The first one-day clash between South Africa and England is now set to get under way at Centurion on Sunday, following Friday's wash-out at The Wanderers, and Hashim Amla will replace Kallis at the top of the order, alongside captain Graeme Smith.
He snared 37 wickets in six Tests against South Africa and Bangladesh over the winter, was an automatic choice in the one-day side and an ever-present in the Twenty20 team which captured England's first world one-day trophy in the Caribbean earlier this month.
England will be seeking to win their first major one-day title after beating Sri Lanka in the semi-finals.
Captain Habibul Bashar top-scored for Bangladesh with 47 and can now look forward to the first two one-day internationals this weekend.
Lancashire all-rounder Andrew Flintoff, a veteran of 129 international ODIs, believes England are close to ending their wait to secure a first major one-day international trophy.
The work reported Wednesday is a first step toward one day growing customized new ears for children born with malformed ones, or people who lose one to accident or disease.
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