Still, the thrill of running First Avenue this year may be muted, somewhat, in the wake of superstorm Sandy.
First Avenue is closed between 42nd Street to 57th Street around the building.
The winner of last year's women's race, Firehiwot Dado of Ethiopia, was more than a minute behind when she emerged on First Avenue.
Only slightly less imposing is the pink granite structure that is Seattle Art Museum (1300 First Avenue) and the 48-foot "Hammering Man" that guards its entrance.
First Avenue, one of the city's major cultural arteries, was hopping with rock stars, delegates, reporters and other conventioneers, despite the storm barreling toward the Gulf Coast.
Granted, few runners have won the race on this particular stretch of the road, but several definitive surges on First Avenue have helped separate marathon champions from also-rans (literally).
"Your decision on First Avenue can make or break your race, " said Meb Keflezighi, the 2009 New York City Marathon champion who finished fourth this year at the London Olympic marathon.
The temptation to surge on First Avenue can come from the feeling of redemption that comes not only from the wall of sound one encounters on the avenue, but from surviving the desolation of the Queensboro Bridge.
Sixty years ago this week, Reverend Martin Luther King, Jr. delivered his first sermon at Dexter Avenue Baptist Church in Montgomery, Alabama.
Green was arrested after the first assault in Dart Avenue, Torquay, but despite being picked out in an identification procedure, he claimed he had an alibi and was released without charge.
Sean Connery also sported a kilt, I assume correctly draped, though whether supported or unsupported I neglected to ask, when he led the parade in 2002, the first time it ascended Avenue of the Americas.
Crew got into the wedding business with its first bridal boutique on Madison Avenue in New York City.
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When crews prepared to drill the giant new cavity under Second Avenue, they first had to freeze the ground to about minus 20 degrees so as not to destabilize the buildings above as the boring machine cut through.
First came a trip to Madison Avenue in 1978 to find an image.
Lawrence became, in the 1960s, the first really powerful female player on Madison Avenue.
Yes, I took a calculated risk that I could be embarrassed and turned away by the Saks buyer, and yes, reaching for the ultimate, the buying office headquarters of Saks Fifth Avenue, to sell my first creation, was a daring move.
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Stars including Jimmy Wong Yue, Ti Lung and Tso Tat-wah were the first to model their hands for the, Avenue of Stars, modelled on Hollywood's walk of fame.
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For Sunday' finish, Russia's Viatceslav Ekimov, 40, led the peloton, the main rider pack, as it arrived for the first of eight laps on the famed Paris avenue to honor him as the Tour's oldest rider.
This spring the company opened onMadison Avenue in New York, the first of five planned city-center stores in the U.S. It boasts a latte bar, scores of high-resolution flat-panel displays and a studio for a budding financial news and information operation that serves radio and the Web.
Covering 78 blocks that fan out around Grand Central and up Park Avenue, from East 39th Street to East 57th Street, and from Fifth Avenue as far as Second Avenue, the rezoning proposal was first presented by the Department of City Planning in July 2012 and updated with more details on Feb. 28.
Laurie told me the Park Avenue event hadn't been the first time I'd crossed paths with her grandson Carter.
This is the first time Model Lounge has been at the Park Avenue South location, and it seems to be a perfect fit.
When you first walk into The Big Place on 901 Lincoln Avenue (the largest of the three food-related businesses), you are immediately taken in.
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C. is a building that graces Pennsylvania Avenue with an exterior engraved with the First Amendment to the Constitution and its guarantee of, among other liberties, freedom of speech.
"We have tangible evidence of our first conversation, " he stated, and of the avenue where it all began.
By then, the Times had moved from its old building, on West Forty-third Street, to the sleek Renzo Piano building, on Eighth Avenue between West Fortieth and West Forty-first Streets.
The first Nicole Miller boutique opened on New York's Madison Avenue in 1986.
In 1984 Zuckerman and Linde took on their first tower, the 50-story edifice at 599 Lexington Avenue in New York.
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