Do your homework on the Internet and through contacts to find out their strengths, weaknesses, biases, curiosities, and insecurities, Knowledge is power, and that can be used for leverage.

FORBES: Don't Let Investor Negotiations Kill Your Startup

Tapeworm parasites have had their genetic code mined for weaknesses in an effort by an international team of researchers to find new treatments.

BBC: 'Weakness mining' for tapeworm drugs