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Individuals may suffer from high levels of fatigue, muscle or heart weakness, diabetes, strokes, or vision and hearing loss.
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Those planning on flying this holiday may experience short-term side effects from fatigue and increased cortisol levels, the report details.
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John Davis, an HBS management professor and faculty chair of the Crossroads Program, says many bosses lack "good thermostats" for gauging their levels of fatigue.
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LoRusso says a good way to check your sleep habits is to note your levels of fatigue during the day and jot down other symptoms you might be having.
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The report also notes that those who chose to reply might have been biased towards reporting higher levels of fatigue in order to avoid the potential threat of new, more relaxed regulations.
BBC: One in five pilots 'suffers cockpit fatigue'
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In the latest StressPulseSM survey by ComPsych Corp, which provides employee assistance programs, 63% of the employees polled said they had high levels of stress with extreme fatigue and feeling out of control.
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But steel alloys subjected to cyclic stress levels below their endurance limit rarely fail as a result of fatigue.
ECONOMIST: Aircraft fatigue