French for "fat liver, " this delicacy comes from ducks and geese that are fed massive amounts of food in the last weeks of their life.
Kynamro carries a Boxed Warning on the serious risk of liver toxicity because it is associated with liver enzyme abnormalities and accumulation of fat in the liver, which could lead to progressive liver disease with chronic use.
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The CHMP was also concerned by liver test results in patients taking Kynamro showing a build-up of fat in the liver and increased enzyme levels, and was not convinced that the company had proposed sufficient measures to prevent the risk of irreversible liver damage.
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But it also caused diarrhea and a buildup of fat in the liver, which could mean liver damage.
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In a long-term extension trial one-quarter of mipomersen-treated patients had an average liver fat fraction greater than 20%.
Prevalent in the UK, the US and Australia, obesity is linked to diabetes, which can be connected to a build up of fat in the liver.
Aside from restrictions placed on it by the FDA (for instance, it will be sold only through a single mail order pharmacy), the drug causes the buildup of fat in the liver, a warning sign that it may also cause liver damage.
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As a result, the fat accumulates in the liver, spleen and bone marrow, causing bone damage, anemia and possibly death.
Elevations in liver enzymes and hepatic (liver) fat were also observed.
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Raw whale-meat bacon (a.k.a. blubber) was white, hard to swallow and tasted like pork fat injected with cod-liver oil.
The balance of protein and carbohydrate and fat -- the cod liver oil.
Alcohol may increase levels of hepatic fat and induce or exacerbate liver injury.
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All of these drugs work by inhibiting the same liver enzyme, thereby preventing the liver from turning fat into cholesterol.
The process of detoxification allows the liver to convert fat solubles stored in our cells into water-soluble substances that can easily be excreted.
It is not nearly as powerful as current cholesterol drugs like Merck's Zocor and Pfizer 's (nyse: PFE - news - people ) Lipitor, which work by preventing the liver from turning fat into cholesterol.
Given by itself, it is less powerful than current cholesterol drugs like Merck's Zocor and Pfizer 's (nyse: PFE - news - people ) Lipitor, which work by preventing the liver from turning fat into cholesterol.
It is metabolized by the liver and converts to fat more easily than any other sugar.
Right now, the gold standard in cholesterol medication is a class of drugs called the statins, which prevent the liver from making cholesterol from fat.
It often means that there is a greater likelihood that the body is storing fat around the internal organs such as the liver and kidneys, which increases the chances of getting heart disease.
The decadent sauce is ladled over cheese curd-dotted chips fried in duck fat and topped with 100g of expertly seared goose liver.
That's because they store fat in their livers (as in cod-liver oil).
When you have a lot of excess fat, it generates so much free fatty acid, the liver can't handle it, so it stores it.
The workhorse liver cells, called hepatocytes, sit next to cells that store fat, immune cells and endothelial cells.
The liver, in the center of the bird's body, stores fat the bird traditionally uses on long migratory flights.
On Thursday, for instance, two companies made their rebut in NASDAQ, Kythera Biopharmaceuticals (NASDAQ:KYTH) that develops a drug for face fat reduction, and Intercept Pharmaceuticals (NASDAQ:ICPT) that focuses on the treatment of chronic liver diseases Both stocks traded above their IPO prices in early afternoon trade.
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The French scientists looked at 163 non-drinkers who had fatty livers - where fat deposits build up in the organ, potentially leading to formation of fibrous tissue and then to cirrhosis or even liver cancer - to see how many of them had the sleep disorder.
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