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Wes Anderson's Fantastic Mr Fox, which featured the voices of George Clooney and Susan Sarandon, kicked off the event in 2009.
BBC: Tim Burton's Frankenweenie to open London Film Festival
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Fantastic Mr Fox goes up against films including the Coen Brothers' A Serious Man, Abbie Cornish's Bright Star and Viggo Mortensen's The Road.
BBC: John Hurt to be made BFI fellow
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Fantastic Mr Fox opens the London Film Festival on 14 October.
BBC: A look at the fantastic sets of Mr Fox
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By that point, Dahl had already published some of his most famous works including James and The Giant Peach, Charlie and the Chocolate Factory and Fantastic Mr Fox.
BBC: Profile: Quentin Blake
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Up, which opened last summer's Cannes Film Festival, has also been nominated for best animation and is up against Coraline, 9, Fantastic Mr Fox and Disney's forthcoming Princess and the Frog.
BBC: Avatar, Star Trek and District 9 lead award shortlist
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Now, in the infectiously primitive talking-animal world of "Fantastic Mr. Fox", he's become an ironic realist.
CNN: Review: 'Mr. Fox' is fantastic
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With its virtuoso tomfoolery, "Fantastic Mr. Fox" is like a homegrown Wallace and Gromit caper.
CNN: Review: 'Mr. Fox' is fantastic
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Wes Anderson, creator of the rascally stop-motion fable "Fantastic Mr. Fox", turns out to be born to make animated films.
CNN: Review: 'Mr. Fox' is fantastic