Our research also indicated that 2000-2003 seems to be a time when failure fatigue had set in.

FORBES: What Can We Learn from a Culture of Failure?

This relieves the symptoms of extreme breathlessness and fatigue associated with severe heart failure.

BBC: Image of heart failure

Testimony at the hearings also revealed that fatigue apparently contributed to the failure of Renslow and First Officer Rebecca Shaw to save the plane as it approached Buffalo Niagara International Airport.

CNN: FAA orders review of regional airlines' training