The current face transplant patient understood the risk of rejection and of immunosuppressants, doctors said.
In April 2010, a patient identified only as "Oscar" received the first ever full-face transplant in Spain.
By 2004, Siemionow was looking for the right candidate for a face transplant who wasn't doing it for vanity.
One of the French face transplant recipients was a man who had a genetic disorder that created large tumors on his face.
The first partial face transplant took place in November 2005 in France.
In order for the face transplant to work, nerves that control feeling and movement would have to be attached to be successful.
There's one other patient in line for a face transplant through the same Department of Defense grant that funded Wiens' procedure, Janis said.
Some candidates for a face transplant are survivors of trauma, such as burn or accident victims, who have exhausted all other reconstructive possibilities.
European news media recently reported that a surgeon in Spain received approval for another face transplant, which would be the fifth in the world.
Connie Culp received the first near-total face transplant in the U.S. She was injured by a bullet in 2004 when her husband shot her.
Connie Culp of Ohio also represented a face transplant milestone, receiving a transplant of more than 80% of her face at the Cleveland Clinic in December 2008.
Doctors chose a woman who survived a shotgun wound to her face as the first recipient of a face transplant after treating her for nearly four years.
Siemionow, who has been working on face transplant research for 20 years, received approval from the Institutional Review Board in 2004 to conduct a full facial transplant.
They practiced face transplant operation on cadavers several times.
CNN: How gunshot survivor became first to receive face transplant
The woman who received the first-ever near-total face transplant in the United States told her doctor she has regained her self-confidence, said Dr. Maria Siemionow, head of plastic surgery research at the Cleveland Clinic and leader of the transplant team.
Currently, cancer patients are not candidates for face transplants because transplant recipients must take immunosuppression drugs for life so that the body does not reject the donated tissue, Siemionow said.
The lessons were before the transplant, when her face was so badly disfigured, but still he fell in love with her.
In 2007, a French team performed the third partial facial transplant on a man who was disfigured by a genetic disorder that created large tumors on his face.
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