Turning any extremophile into drugs would likely require cloning their antibiotic molecules and manufacturing them with help from a more suitable carrier organism.

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This super-extremophile, using genetic instructions from a few different microbes, would create a complex a molecule called Acetyl Coenzyme-A, or Acetyl Co-A for short.

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Now researchers at North Carolina State University and the University of Georgia will try to create their own version of an extremophile, one unlike any found even in the most extreme places--a bug that will create fuels like butanol or ethanol.

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This is the theory that life is not merely a surface scum which clings to the outside of planet Earth, but that living things, in the form of so-called extremophile bacteria which can tolerate infernal heat, penetrate several kilometres into the planet's interior.

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Caves were thought to be essentially devoid of life until six years ago, when the renowned University of Colorado microbiologist Norman Pace, also an avid caver, discovered a way to identify extremophile microorganisms by cloning and sequencing unique sections of their DNA. Prior to Pace's work biologists had fruitlessly tried to cultivate these microorganisms with traditional lab techniques using nutrient-rich petri dishes.

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