They experience fewer ups and downs and endure less stress and worry about the possibility of layoffs and loss.

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We expect there to be corrections in the price of oil throughout 2012, just like the ups and downs commodities experience from year to year.

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Also, over decades of experience doctors have gotten to know the ups and downs of tamoxifen extremely well.

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He also accepted the significant ups and downs that the country would experience along the way.

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Novartis may be wise to seek a measure of stability in an industry beset with ups and downs, but it could experience some unwelcome side-effects.

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Her ups and downs are the same that any healthy person would experience -- as long as the battery in the stimulator implanted under her collarbone remains charged.

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Then on 17 June, after a season of struggle and many ups and downs, Ablett left the club but insists it is an experience he can look back on with fondness.

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