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Doctors found that those on exemestane were less likely to see the disease return.
BBC: Drug 'boosts breast cancer fight'
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This latest study, which involved women from 37 countries, examined whether switching to exemestane could benefit these patients.
BBC: Drug 'boosts breast cancer fight'
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Three aromatase inhibitors are set for tentative approval - anastrozole, exemestane and letrozole.
BBC: Earlier use of cancer drug backed
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Doctors also found that taking exemestane reduced the risks of developing cancer in the other breast or in the uterus.
BBC: Drug 'boosts breast cancer fight'
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Exemestane is licensed in the UK. However, at the moment it is only given to women with advanced breast cancer who won't benefit from surgery.
BBC: Drug 'boosts breast cancer fight'
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One continued taking tamoxifen while the other took exemestane.
BBC: Drug 'boosts breast cancer fight'
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"Though recurrence of breast cancer in women taking tamoxifen was already low, our results show that switching to exemestane can reduce that number by about a third, " said Judith Bliss of Cancer Research UK, one of the study authors.
BBC: Drug 'boosts breast cancer fight'
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"Women switching to exemestane had fewer cases of cancer in the other breast, which also suggests that taking the drug after tamoxifen may be a better way to prevent breast cancer than taking tamoxifen alone, " said Professor Charles Coombes of Imperial College London, the study's lead author.
BBC: Drug 'boosts breast cancer fight'