Computers have retrieved the mythologizing of numbers, attribution of mystical powers to mathematics, and cultivation of esoteric knowledge.

FORBES: Does Analytics Make Us Smart Or Stupid?

But none of his esoteric knowledge could substitute for the multidimensional grasp of space and form and the strength and clarity with which the tensions and relationships of structure and style are expressed that are the architect's innate, creative genius.

WSJ: Philip Johnson: Short of Attention Span, Long on Aesthetics

The Higgs boson feels untouchably esoteric, a fragment of pure knowledge that may never be applied in the practical world.

WSJ: Matt Ridley on the Higgs Boson | Mind & Matter

Such knowledge may not be entirely esoteric.

ECONOMIST: Here be serpents