The anti-flush drug, they argued, is untested, and its potential cardiovascular effects are unknown.
Laboratory modification introduces alien and unnatural genes into crops, it is argued, where their eventual effects are unknown.
Other risks include the unknown effects that healthcare reform will have on drug companies.
If used in humans, these hybrid cells could have unknown effects on the body.
An existing and extensively tested anesthetic was shown to have previously unknown effects.
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No presses are required for purely electronic publishing, and over time, this new distribution system will have as-yet-unknown effects on the traditional publishing world.
Doubts about whether Cordaptive has unknown side effects--or somehow dulls the effectiveness of niacin--are the main threat to its success.
Because of the potential for unknown side effects, "it is untenable to recommend a drug or nutraceutical in the absence of efficacy evidence simply because it could possibly help and initially appears harmless, " Lon S. Schneider, M.
Because of the nature of the business, cover written 10, 20 or even 50 years ago can be called upon to pay out massive damages today the prime example being asbestos, the harmful effects of which were unknown when it was first used as an insulation material.
And, of course, the problem of accounting for unknown adverse effects has never been more acute for the drug industry, with intense and costly political controversies over the safety profile of drugs like Vioxx and Avandia leading to panic among patients, outrage among politicians, and the inevitable endgame of costly withdrawals and lawsuits.
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She warned women not to take too many antioxidants - as this could have unknown side-effects.
Abramson and other critics argue that the rush to give cholesterol drugs to just about everyone goes beyond the evidence and could pose unknown future side effects.
Despite the fact that these drugs have been on the market for more than two decades, like any class of drugs that are prescribed for chronic use, their effects over decades of use are unknown.
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"Despite a considerable amount of research into the effects of legal highs, much is still unknown about their longer-term impact, " she said.
If drug developers could better target their inhibitors farther down the prostaglandin chain, they might produce powerful drugs that could fight pain and avoid unknown, possibly fatal, side effects.
The effects of brain activity being artificially stimulated are still unknown.
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