Race to the Top has helped drive states nationwide to pursue higher standards, improve teacher effectiveness, use data effectively in the classroom, and adopt new strategies to help struggling schools.

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To do this, we need to invest in systems - software and resources that create and deliver engaging interactive courses, monitor use, effectiveness and engagement in new ways and share that information with teachers and educators.

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But Iressa failed to prove its effectiveness in a large clinical trial, and its use was severely curtailed.

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Indeed, Mr. Brill fails to tell readers that by law, Medicare is not allowed to use cost-effectiveness as a criterion in determining what services to cover.

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"Similar technologies are limited by cost of materials, use of noxious chemicals in the application or loss of effectiveness after a few washings, " said Gennaro Gama from the University of Georgia Research Foundation (UGARF).

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American entrepreneur Malcolm McLean invented the shipping container in 1956, but it took a decade for its stunning effectiveness to be revealed as it went to use supplying the military during the Vietnam War.

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Not only did government regulators underplay scientific evidence of the effectiveness and relative safety of DDT, they also failed to appreciate the distinction between its large-scale use in agriculture and more limited application for controlling carriers of human disease.

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