And researchers and Wall Street analysts have had another reason for viewing it as an also-ran: It is only half as effective as torcetrapib, boosting HDL by only 30%.
But one of the most effective workouts takes less than half an hour.
Fly-half Arlidge was highly effective with kicks out of hand, but had an off-day in front of the posts, failing with his conversion attempt of Fussell's try.
Since that day, Jonny Wilkinson has returned to the side at fly-half and formed an effective combination with Mike Catt -- he is expected to shrug off a groin problem -- while the likes of Simon Shaw and Andrew Sheridan have been inspirational up front.
Even the most proven, effective treatments are only given to patients half of the time.
Half rated a promotion as the most effective way to get them to stay put.
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Another strong point was the effective use of sound, especially in the first half where Suffolk was descending into a 'new Ice Age'.
Relations with major financial institutions such as the International Monetary Fund have improved, particularly in the light of more effective revenue collection -- up by about a half following the introduction of a consumption tax last year.
An edgier but highly effective path to cost-cutting is literally cutting pills in half.
It proved effective as Cassano was substituted by Italy Coach Cesare Prandelli at half time.
It has also estimated a quarter of people living with HIV in London remain undiagnosed and half of people are diagnosed too "late" for effective treatment to be carried out.
After his debut half century, Australian Twenty20 specialist David Warner did not prove so effective on his second appearance, making only 19.
For example, the student visa system, which admits half a million non-EU students a year, needs a much more effective means of testing whether the applicants are genuine and intend to return home.
Carotid surgery began over a half-century ago, and studies by the 1990s clearly showed it was more effective than existing drug therapy at preventing strokes.
Jamie Roberts and Brian O'Driscoll have also struck up an effective midfield partnership while McGeechan has opted for Welsh pair Stephen Jones and Mike Phillips in the half-backs.
With almost half of all Scots experiencing cancer at some point in their life, ensuring swift and effective treatment is critical.
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Still, the CDC's David Shay said the 1994 study that took a group of people and gave half of them a placebo and half of them have a vaccine is solid enough evidence that the flu vaccine is very effective.
Over half rate e-mail as essential to their work and most agree that e-mail is effective for both the simplest of tasks and for more complicated projects.
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