"The effectiveness of acupuncture for (seasonal allergies) compared with other antiallergic interventions and the possible underlying mechanisms of any effect, including context effects, need to be addressed in further research, " they write in the study.
The word antidepressant covers a wide range of medications that have very different mechanisms of action and very different side effect and risk profiles.
Though the placebo effect remains largely shrouded in mystery, researchers attribute some aspects of the placebo response to active mechanisms in the brain that can influence bodily processes such as the immune response and release of hormones.