They found that a genotype conferring low levels of the enzyme monoamine oxidase A (MAOA), when combined with early child abuse, predisposed the individual to later antisocial behavior.

WSJ: Neurocriminology: Inside the Criminal Mind

Early-stage tests have shown that the compounds penetrate artery walls and block the bad enzyme.

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As Genzyme did in its early days, BioMarin focuses on drugs for rare genetic diseases, usually those in which one enzyme is defective.

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