In the early 1990s he saw a PBS program on the microprocessor and Intel and hit upon another notion: Why not design a microchip for drug release?
Katy Swaine, head of legal services at drug charity Release, thinks there is some ambiguity about what constitutes a medicinal form of the drug.
Chief executive Ryan Howard plans to mine what he says is a database of 40 million patients by, for example, helping pharmaceutical companies enroll patients in clinical trials, or monitoring a drug following its release on the market.
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The latest iterations, "drug-eluting" stents, release a chemotherapy-type drug.
This property will be used to load and release the drug, making treatment instantaneous and effective.
In the study where it helped patients lose weight, the drug also raised good cholesterol, or high-density lipoprotein (HDL), by 23%, almost as much as Niaspan, the sustained-release niacin drug made by Kos Pharmaceuticals (nasdaq: KOSP - news - people ) that is the main currently available treatment for raising HDL. Rimonabont also cut triglycerides, another risk factor for heart disease, by 16%.
Hassan did not speak on the company's conference call, and he did not point to any promising candidates in its drug pipeline in the press release.
Tredaptive is a drug which combines extended-release niacin with laropiprant.
FORBES: Will Merck's Failure With Tredaptive Impact How Drugs Are Approved in Europe?
Another bill would increase supervision and drug testing of offenders after release from jails in England and Wales and open up the Probation Service to private competition in an effort to cut reoffending rates.
In a bewildering result, an experimental drug aimed at reducing inflammation in the arteries failed in a big clinical trial but prevented heart attacks, strokes and deaths, according to a press release from the drug's maker.
Selling a delayed-release version of a drug is a common way to do this.
The HPA said it would not release details of the drug user's sex or age due to patient confidentiality.
The practice involves pharmaceutical manufacturers paying generic manufacturers to delay the release of a generic drug in anticipation of the patent cliff.
This morning, the drug giant confirmed in a press release that it is renegotiating the safety information on Eprex's label in France.
That's good news for Andrx, which hopes to sell its delayed-release lovastatin as a new drug under the brand name Altocor.
Ranbaxy, an Indian drug firm, has developed controlled-release systems that allow patients to take only one pill a day instead of several small doses.
Novartis hopes that LAF237 combined with metformin will provide patients with more lasting glucose control. (The company is also testing the drug on its own, and will release data on June 8).
The ill-fated diet drug fenfluramine, for example, stimulated dopamine release within the hypothalamus and had the paradoxical effect of reducing appetite.
This morning Sarepta Therapeutics put out a press release detailing the results of a drug that actually seems to help boys with muscular dystrophy walk farther on a six minute walk test.
FORBES: The Breathtaking Slide From Sarepta's Muscular Dystrophy Study
Usually, delayed-release formulations are a way for big drug companies to keep generic firms at bay.
Shire no longer produces the instant release (IR) form of the drug.
Bydureon is an injectable, extended-release version of Amylin's older diabetes drug, Byetta, which is injected twice daily.
WSJ: FDA Approves Amylin's Bydureon Diabetes Drug After Delays
Four other men apprehended in the operation also were brought to New York for trial, the Drug Enforcement Administration and federal prosecutors said in a joint release.
To get around the problem of addicts failing to follow a drug regimen, DrugAbuse Sciences is developing a controlled-release version of naltrexone that requires only a monthly injection.
But Amgen will release a follow-up version of the drug called Aranesp that needs to be taken less often and is expected to grab a lot of the anemia market.
Technical tinkering, such as changing the formulation of a drug from a fast-acting pill to a slow-release system, is a common tactic.
Kos was founded by veteran drug executive Michael Jaharis in 1988 to sell a delayed-release niacin that would cause less flushing than earlier versions.
However, the Prison Service, in which healthcare is overseen by the South-Eastern Trust, has distributed 35 packs of the drug to prisoners judged to be at risk of overdose on release.
BBC: Life-saving drug not administered by two NI health trusts
James Stein, a cardiologist at the University of Wisconsin, Madison, said before the release of the SEAS study that he believes any drug that lowers the bad cholesterol, or LDL, by 20% as Zetia does is likely to help patients, but that the benefit for Zetia is still unproven.
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