It did not matter which medicine drug patients took so long as both inflammation and cholesterol were reduced.
Pfizer has shelved its most promising experimental drug because the medicine increased the risk of death in a giant clinical trial, a disaster for the world's largest drug company.
These expenses visits to medical professionals as well as any medicine or drug which requires a prescription of a physician for legal use.
Farmeron is a Web data service that farmers can use to aggregate the troves of information produced about their animals: diet, health, reproduction, milk production and medicine or drug dosage.
Like medicine, drug discovery was described as something that used to be an art but now was a science, and thus amenable to industrialization, and well-positioned to reap the associated benefits: economies of scale, benefits of standardization, robust metrics, etc.
FORBES: Want to Industrialize Healthcare? Ask How Well It Has Worked for Pharma R&D
In summary, Precision Medicine, defined as rules (algorithm) based medicine by Clayton Christensen seems on the horizon, where medicine and drug discovery will ultimately be supported by intelligent systems (compare Watson) that will enable completely new therapeutic concepts, not least with the advent of mobileICT-based companion (monitoring)diagnostics.
FORBES: Does Pharma's Innovation Difficulties Reflect Bad Leaders or Tough Circumstances?
For any drug, be it a new medicine to treat diabetes in millions of patients, or a drug to treat a rare disease afflicting only a few thousand people around the world, intense discussions and analyses are carried out to determine how best to price such a drug.
Bristol-Myers Squibb (nyse: BMY - news - people ), which spent years between drug approvals, last year had a promising new schizophrenia medicine approved and may get an AIDS drug onto the market this year.
Will the new drug change the practice of medicine such that patients will no longer face costly hospital procedures?
That drug combines Zocor with another medicine, Zetia, to lower cholesterol substantially--potentially without the muscle-harming side effects of the statins.
GlaxoSmithKline's own analysis of its diabetes drug Avandia showed that the medicine increased the risk of heart attacks by a third.
Pfizer 's most important experimental drug, a new heart medicine designed to clear plaque from the arteries, has also been it's most controversial.
India's patent office rejected the company's patent application, arguing the drug was not a new medicine but an amended version of its earlier product.
Pfizer also said this morning that the Food and Drug Administration refused to accept a new drug application for an experimental medicine the company got from its acquisition of FoldRx.
FORBES: Pfizer's Capsugel Sale Could Set Stage For Other Divestitures
They showed that Vytorin, a combination of the generic cholesterol drug Zocor and the newer medicine Zetia, did not reduce ultrasound readings of thickness in the neck artery any more than Zocor alone.
FORBES: Merck To Pay $688 Million To Shareholders For Delaying Vytorin Results
But news of a delay for Takeda's lead experimental medicine, a drug aimed at lowering cholesterol even more than current blockbusters like Lipitor, Crestor and Vytorin, should worry anyone connected with the drug industry.
Novartis says it hopes next year to apply for approval for three additional drugs for various tumors types, including a new treatment for ovarian cancer, a new lymphoma medicine and a drug for Cushing's disease, a benign tumor in the pituitary gland.
AstraZeneca lost the ulcer medicine Prilosec, the world's top drug before Lipitor earned the title, by replacing it with a similar medicine, Nexium, and launching a bunch of other drugs that, while not breakthroughs, had clear advantages over rivals.
In both cases he sold the company that developed the medicine to a larger drug maker.
The findings illustrate the potential for a new era of genomic medicine, in which drug regimens are tailored to fit a person's genetic risk factors.
It used to be gospel among drug safety experts that once a medicine was approved, there was nothing the FDA could do to limit its use.
Recent studies published in The New England Journal of Medicine indicate that the drug has potential, but more studies must be done to confirm the results.
Also exciting: a stop-smoking pill, a long-delayed inhaled insulin, an osteoporosis medicine, a sleep drug and an antibiotic that can treat infections in a single dose.
In the most restrictive cases, only certain registered doctors are allowed to prescribe a medicine, or a drug is only distributed by a limited number of pharmacies.
At my initial diagnosis I participated in a clinical trial evaluating Herceptin, a so-called personalized medicine (PM) drug targeting a mutation believed to be driving my cancer.
FORBES: A Dying Cancer Patient's Plea For Personalized Medicine
Schering (nyse: SGP - news - people ) is stumbling badly because sales of its allergy drug Claritin have plummeted as the medicine became available without a doctor's prescription.
For the company's finances, the most important new drug is torcetrapib, a new medicine designed to raise high-density lipoprotein (HDL), the "good cholesterol, " which is thought to help clear plaque from the arteries.
Researchers from MD Anderson Cancer Center and elsewhere are reporting today in the New England Journal of Medicine that the Incyte drug, called INC424, improved symptoms of about 75% of 153 patients with myelofibrosis.
In the long term, researchers hope a detailed understanding of the genome's permutations will lead to a new era of customized medicine, in which drug regimens, diagnostic tools and medical devices are tailored to individual genetic codes.
Marcia Angell, a lecturer at Harvard University, former editor of The New England Journal of Medicine and author of The Truth About Drug Companies, wrote in an e-mail that ghostwriting practices are "evidently very common" in medicine.
应用推荐